SURFSeq Q is an ultra-high throughput sequencer with a worldwide superb daily data output capacity. By integrating several innovative technologies, such as high-speed chemistry, new patterned array sequencing flow cell, AI base recognition algorithm, and other innovative technologies, SURFSeq Q can achieve the Q40 score >=90% with a powerful productivity of 9Tb per day in a single run. Its superior data delivery capabilities and high accuracy can efficiently support scientific discovery and sequencing services, such as extensive population cohort studies and single-cell and spatial omics research.